Aryldialkylphosphatase

An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).

Also Known As:

Paraoxonase; Aryl-dialkyl Phosphatase; Arylalkylphosphatase; Homocysteine Thiolactone Hydrolase; OPA Anhydrase; OPH Enzyme; Organophosphorus Acid Anhydrase; Organophosphorus Acid Anhydrolase; Organophosphorus Acid Hydrolase; Organophosphorus Hydrolase; Paraoxonase-1; Paraoxonase-2; Acid Anhydrase, Organophosphorus; Acid Anhydrolase, Organophosphorus; Acid Hydrolase, Organophosphorus; Anhydrase, OPA; Anhydrase, Organophosphorus Acid; Anhydrolase, Organophosphorus Acid; Aryl dialkyl Phosphatase; Enzyme, OPH; Hydrolase, Homocysteine Thiolactone; Hydrolase, Organophosphorus; Hydrolase, Organophosphorus Acid; Paraoxonase 1; Paraoxonase 2; Phosphatase, Aryl-dialkyl; Thiolactone Hydrolase, Homocysteine

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Esterases: 1594
      - Phosphoric Triester Hydrolases: 13
        Aryldialkylphosphatase: 1912

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Disease

Drug/Important Bio-Agent (IBA)